CREATIVE WRITING

Creative Writing: Reply to Francesca in Regards to Proton Pump Inhibitors

The previous discussion response does exhibit a comprehensive understanding of the medical condition and how Proton pump inhibitors work well to combat it. However, pieces of information were still new to me, such as pH working with the pump inhibitors and their reactions to gastroesophageal reflux disorder (GERD). After researching further, it has been corroborated that GERD symptoms are reduced, and the healing in mucosal operations is witnessed when the suppression of pH is > 4.0 in intragastric acid for several hours (Gasiorowska, 2017).

Moreover, the proton pump inhibitors have created effectiveness because the previously used one released a stimulation in hormonal stimuli during the meal (Gasiorowska, 2017). The antisecretory impact of inhibitors is insignificant in the beginning as all pumps are activated in postprandial secretion. The balance might be more evident in another three to five days when the additional proton pumps have been inhibited, and a balance between inhibited and blocked protons has been achieved. The maximum positive effect, up to 70%, is obvious after using proton pump inhibitors for at least five days.

I agree that the symptoms of GERD are efficaciously controlled with the inhibitor pumps as the parietal cells are inhibited from releasing acid secretion, stopping the acid from flowing back into the organs. I also agree with the information that long-term use of inhibitor pumps would create reactions within the patients body in the form of diarrhea, deficiency of vitamin B12, acute interstitial nephritis (AIN), and related problems (Ambizas & Etzel, 2017). It depends on the accurate guidance from the pharmacists regarding the usage and indications for the pump inhibitors so that patients know how much quantity and for how long it would serve as an effective remedy rather than a disaster for health in the long run. Self-monitoring of pumps and dosage instructions is crucial for gaining positive patient outcomes.

References

Ambizas, E.M. & Etzel, J.V. (2017). Proton pump inhibitors: Considerations with long-term use. US Pharmacist, 42(7), 4-7.

Gasiorowska, A. (2017). The role of pH in symptomatic relief and effective treatment of gastroesophageal reflux disease. Przeglad Gastroenterologiczny,12(4), 244249. https://doi.org/10.5114/pg.2017.72097